Vancomycin can cause two types of hypersensitivity reactions, the red man syndrome and anaphylaxis [2]. Red man syndrome is an infusion-related reaction peculiar to vancomycin [3]. …
Effects of mechanical ventilation on the interstitial extracellular ...
Oct 31, 2025 · Background Mechanical ventilation, a lifesaving intervention in critical care, can lead to damage in the extracellular matrix (ECM), triggering inflammation and ventilator …
Chest radiography versus lung ultrasound for identification of …
Background Lung ultrasound may be a reasonable alternative to chest radiography for the identification of acute respiratory distress syndrome (ARDS), but the diagnostic performance …
The role of programmed cell death in organ dysfunction induced …
Jul 10, 2025 · Sepsis is a life-threatening condition resulting from pathogen infection and characterized by organ dysfunction. Programmed cell death (PCD) during sepsis has been …
COVID-19 ARDS is characterized by higher extravascular lung …
Background In acute respiratory distress syndrome (ARDS), extravascular lung water index (EVLWi) and pulmonary vascular permeability index (PVPI) measured by transpulmonary …
Disseminated intravascular coagulation with increased fibrinolysis ...
Background There is evidence to demonstrate that the coagulopathy which occurs in patients with traumatic brain injury coincides with disseminated intravascular coagulation (DIC). We …
Vasoplegic syndrome following cardiothoracic surgery—review of ...
Vasoplegic syndrome is a common occurrence following cardiothoracic surgery and is characterized as a high-output shock state with poor systemic vascular resistance. The …
Clinical review: The critical care management of the burn patient ...
Between 4 and 22% of burn patients presenting to the emergency department are admitted to critical care. Burn injury is characterised by a hypermetabolic response with physiologic, …
Hyperferritinemic sepsis, macrophage activation syndrome, and …
Background One of five global deaths are attributable to sepsis. Hyperferritinemic sepsis (> 500 ng/mL) is associated with increased mortality in single-center studies. Our pediatric research …
Liberal versus restrictive transfusion strategies in subarachnoid ...
The optimal hemoglobin (Hb) threshold to trigger red blood cell transfusions (RBCT) in subarachnoid hemorrhage (SAH) patients is unclear. This study evaluated the impact of liberal …