Jun 8, 2025 · In the heart, electrical impulses are generated by specialised pacemaker cells and spread across the myocardium in order to produce a co-ordinated contraction in systole. An …

In most humans, these cells are concentrated in the sinoatrial (SA) node, the primary pacemaker, which regulates the heart’s sinus rhythm. Sometimes a secondary pacemaker sets the pace, if …

Jul 30, 2025 · Pacemaker cells are cardiac muscle cells that possess automaticity, meaning they can spontaneously generate electrical impulses without external nervous system input. Unlike …

Action potentials are considerably different between cardiac pacemaker cells and cardiac muscle cells. While Na + and K + play essential roles, Ca 2+ is also critical for both types of cells. …

Aug 6, 2025 · The primary pacemaker cells in the heart include the sinoatrial node (SAN) cells, atrioventricular node (AV node) cells, and specialized conduction system cells including those …

The characteristics of action potentials differ significantly between cardiac conduction cells, like the SA and AV nodes, and cardiac contractile cells (non-pacemaker cells), such as the …

Pacemaker cells, also known as cardiac pacemaker cells, are specialized cells located in the heart that generate and propagate the electrical impulses that control the rhythmic contraction …

Nov 6, 2025 · The sinoatrial (SA) node is a collection of specialised cells (pacemaker cells), and is located in the upper wall of the right atrium, at the junction where the superior vena cava …

Jul 16, 2021 · Pacemaker cells comprise a small population of specialized cardiomyocytes within the sinoatrial node (SAN) that spontaneously fire to trigger each heartbeat.

Pacemaker cells are highly specialized myocardial cells whose intrinsic ability to rhythmically depolarise and initiate an action potential is responsible for the basal heart rate.