No adverse events occurred during treatment, and the patient's underlying comorbidities remained stable. Sequential therapy with spesolimab followed by dupilumab can be an effective and safe strategy ...

The mechanisms identified in extra-palmoplantar PPP mirror the pathogenic processes in GPP, suggesting overlapping pathways that could inform treatment strategies. The interleukin-36 (IL-36) pathway, ...

A 27-year-old woman reported a history of recurrent flares of erythematous lesions associated with pustules since the ageof 11. She was diagnosed with GPP at the age of 21, during the second trimester ...

Vaccines are commonly made of killed, weakened, or parts of a virus which can stimulate the body's immune system. Normally, in response to vaccine administration, immunoglobulins are formed which are ...

ON JANUARY 15, 1947, the Army Hospital at Wiesbaden, Germany, received a patient with the presumptive diagnosis of smallpox. The patient, a War Department civilian employee, was transferred by ...

Generalized pustular psoriasis (GPP) is a potentially life-threatening disease, which, until recently, had no clear guidance for diagnosis. At IFPA 2024, Siew Eng Choon, MD, from Monash University ...

Study published in Journal of Cosmetic and Laser Therapy highlights the TheraClear ® X photopneumatic device as an effective treatment option, either as monotherapy or in combination with topical or ...

An international consensus statement on generalized pustular psoriasis (GPP) from the International Psoriasis Council (IPC) includes the recommendation that considerations such as body surface area ...

NEW YORK – Laboratory Corporation of America and the US Centers for Disease Control and Prevention received Emergency Use Authorizations from the US Food and Drug Administration last week for a sample ...

Recently, I had a patient with a germline loss-of-function mutation in the interleukin-36 receptor antagonist gene present to my clinic with a rapidly progressive generalized pustular psoriasis (GPP) ...