Degenerative aortic stenosis (AS) has become the most common valvular heart disease and the definitive treatment of symptomatic, severe AS is surgical valve replacement. In the absence of symptoms, ...

Because life expectancy and the prevalence of risk factors such as hypertension, obesity and diabetes are rising globally, heart failure (HF) is growing into a major health problem. Impairment of left ...

The CHARM program consisted of 3 component trials that compared candesartan with placebo in patients with symptomatic heart failure. Two trials randomized patients with LVEF ≤ 40%: CHARM-Alternative, ...

Systolic heart failure is when the left ventricle of your heart, which pumps a lot of your blood, becomes weak. (Photo Credit: cono0430/Shutterstock) What Are the Common Causes of Systolic Heart ...

Background: Prolonged steady state exercise can lead to a decrease in left ventricular (LV) function as well as promote the release of cardiac troponin T (cTnT). There is limited information on the ...

Credit: Getty Images Worsening renal function may be associated with left ventricular ejection fraction in patients with acute heart failure. Worsening renal function (WRF) may be associated with left ...

Heart failure is a complex clinical syndrome affecting around 70 million individuals globally. It has a prevalence of 2% in ...

Cardiomyopathy is the leading cause of mortality in patients with DMD. Compared with their healthy counterparts, patients with DMD — including those with preserved left ventricular ejection fraction ...

Aortic regurgitation occurs when blood flows retrograde (backwards) across the aortic valve from the aorta into the left ventricle during diastole. This abnormal backflow of blood leads to pathologic ...

LBBB is linked to electrical abnormalities, causing inefficient heart pumping, dilation, and systolic dysfunction. The study found LBBB associated with increased heart failure risk, surpassing other ...