A rare inherited disorder, Xeroderma Pigmentosum (XP) is a photosensitive condition characterized by high susceptibility to skin cancers. XP follows the autosomal recessive pattern of inheritance.

Our genomic DNA is continuously damaged by endogenous factors such as reactive oxygen species, and also by environmental factors such as ultraviolet light, radiation, and chemicals. Failure to repair ...

Xeroderma pigmentosum (XP) is a rare and devastating genetic disorder characterized by an inability to repair skin damage caused by ultraviolet (UV) light. As a result, patients with XP develop skin ...

Note to editors: CLINUVEL is releasing in-depth infographics and a video explaining the mechanisms of action in XP and the overall DNA repair process. For updates, follow:Twitter | Facebook | ...

A 6-year-old male child of consanguineous parents was seen with a clinical diagnosis of XP. His visual acuity in both eyes (OU) was hand movements close to face. The lid position, congruity, and tear ...

The progress in nucleotide excision repair research could be traced in the journey of cells--from donor, to clinician, to repository, to researcher, and into the literature. The journey began with a ...

Xeroderma pigmentosum (XP) is a rare and devastating genetic disorder characterized by an inability to repair skin damage caused by ultraviolet (UV) light. As a result, patients with XP develop skin ...

Diagnosed with a rare and incurable condition, Nihal is estimated to be 4,000 times more likely to develop skin cancer than unaffected people. Despite this, she remains determined to live an active, ...

XPC protein acts as a sensor to detect various abnormalities in the DNA structure. The faithful repair of DNA is ensured by using the basal transcription factor TFIIH and XPA protein to verify the ...

Q: Is there really a genetic condition that can make someone get skin cancer during childhood? A: I am not sure if you are referring to xeroderma pigmentosum — XP, although there are other ...