Atherosclerosis represents a chronic inflammatory disease characterized by the accumulation of lipid-laden macrophage foam cells within arterial ...

Sepsis is a fatal syndrome characterized by life-threatening organ dysfunction originating from a chaotic and unchecked innate immune response to infection. Notably, macrophages are the master ...

Scientists at Trinity College Dublin have discovered that electrically stimulating macrophages can “reprogram” them in such a way to reduce inflammation and encourage faster, more effective healing in ...

Macrophages rely on lysosomes to balance microbial killing with self-protection, generating reactive oxygen and nitrogen species during phagocytosis. Using platinum nanoelectrodes, researchers at ...

(A) Volcano plot of DEGs in monocytes/macrophages between NC and CRC samples in the GSE164552 dataset. (B) Venn diagrams of common DEGs up- or down-regulated across the six scRNA-seq datasets (NC vs.

Researchers from the University of California, Los Angeles, have discovered that immune cells known as macrophages remain poised to fight repeat infections due to the persistent presence of signaling ...

Macrophages are the specialized phagocytic cells that respond to toxic particle depositions to exert inflammatory and clearance responses. These long-lived immune cells engulf foreign substances like ...