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The life cycle of a protein

A protein’s life is anything but simple. Discover how transcription, translation, folding, modification, and degradation work together to preserve proteome integrity.
In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, ...
Rush hour never ceases at the nucleus’ border. Gene products begin their lives in the nucleus as strands of mRNA that ship out into the cytoplasm, where they serve as templates for protein synthesis.
Propagation of expression noise from mRNA to protein level is influenced by variation in availability of ribosomal machinery.
Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...