CHAMPAIGN, Ill. — Depression is a complex condition correlated with multiple differences in brain function and mechanisms. A new paper spanning known data about the neurotransmitter GABA and its ...

GABA receptors, long recognised principally for their role in modulating neuronal excitability within the central nervous system, are now emerging as pivotal regulators of immune function. These ...

Fragile X syndrome (FXS) is the most common inherited form of intellectual disability. The cause, which has been well-studied, is the loss of fragile X mental retardation protein (FMRP)—a genetic ...

People with the inherited disorder myotonic dystrophy (DM) often experience excessive daytime sleepiness and fatigue, as well as altered responses to anesthetics that can put them at risk for ...

Respirerx Pharmaceuticals Inc.’s lead GABA-A receptor potentiator, KRM-II-81, has advanced to the next level of evaluation within the National Institutes of Health (NIH) HEAL Initiative Preclinical ...

It may be possible to reduce the severity of COVID-19 symptoms with an inexpensive amino acid that could open up new treatment options for patients. GABA is a natural molecule that is available ...

Preclinical studies in mice that model human COVID-19 suggest that an inexpensive, readily available amino acid might limit the effects of the disease and provide a new off-the-shelf therapeutic ...

GRX-917 (deuterated etifoxine) was well-tolerated with no dose-limiting toxicities and only mild adverse effects comparable to that of placebo in both single and multiple ascending doses, as ...