Part of the answer to how and why humans differ from other primates may lie in the repetitive stretches of the genome that were once considered "junk." A new study finds that when a particular type of ...
Large genome-mapping consortia and thousands of genome-wide association studies have identified non-protein-coding elements in the genome as having a central role in various biological processes.
Myc is a highly unstable transcription factor that is destroyed by ubiquitin (Ub)-mediated proteolysis. We have previously identified an amino-terminal ‘degron’ within Myc that signals its destruction ...