Ductal adenocarcinoma of the prostate is a rare, yet aggressive, subtype of prostate cancer that diverges in clinicopathological and genomic characteristics from the more common acinar adenocarcinoma.

Credit: Getty Images Investigators examined 5-year prostate cancer-specific mortality rates associated with 5 histologic subtypes, 4 of them rare. Compared with the dominant subtype, acinar ...

Note benign prostatic glands for comparison on the left (a) (×200). Cribriform pattern is not recognized as HGPIN in the 5 th edition. On immunostain, HGPIN is positive for racemase and basal cell ...